Acute severe colitis associated with fever, severe diarrhea and marked dilatation of the colon (toxic megacolon) in patients with UC may lead to fatal outcomes.
Acute severe colitis associated with fever, severe diarrhea and marked dilatation of the colon (toxic megacolon) in patients with UC may lead to fatal outcomes. Severe infections due to the immunocompromised status of IBD patients or secondary to complications (intra-abdominal abscesses, intestinal perforation, massive intestinal hemorrhage), and thromboembolic events are life-threatening complications described in IBD patients.